Risk assessment of chemical substances: the PARC project partner institute

On 12 and 13 May, the Institute is taking part in the "Partnership on risk assessment for chemical" (PARC) launch meeting. This is a European partnership encompassing all aspects of chemical substances risk assessment.

Coordinated by ANSES, the PARC project has been selected for funding by the European Union "Horizon Europe" 2021-2027 framework program.

As a large-scale partnership (200 partners from 28 countries), it aims to design a risk assessment programme for chemical substances based on latest-generation strategies for better health and environmental protection.

The main areas of involvement of the Institute are:

> "Multisource environmental monitoring": Ineris is a leader in this area and organises action plans that respond to emergent chemical substance risks and to their impact on human health and biodiversity. Particular attention will go to investigating PFAS [perfluoroalkyl or polyfluoroalkyl substances]* and Endocrine Disruptive Chemicals (EDCs) in connection with national strategies concerning EDCs.

> "Hazard Assessment": Above all, the Institute will contribute to elaborating quantitative in vitro/in vivo extrapolation techniques by drawing upon its expertise in experimental (eco-)toxicology and modelling.

> "New approaches in risk assessment": Ineris will ensure operational coordination for cyclical exposure assessment by means of toxico-kinetic models - also known as PBPK models. It will participate in the “Risk Assessment Methodologies Review” activity through methodologies case studies which consider secondary poisoning.



* The perfluoroalkyl or polyfluoroalkyls [also known as perfluorinated and polyfluorinated alkyl substances] (PFAS) constitute a group of more than 4,700 widely-used chemical products of anthropic origin and which concentrate over time in every human being and in the environment. Find out more.