Ineris has played an active role in this work, developing mathematical models for the assessment of endocrine disruptors in humans and zebrafish embryos, as well as experimental work on zebrafish embryos.
He coordinated the working group devoted to the development of in silico mathematical models.
The main modeling outputs of this project are a human PBPK model taking into account exposure to endocrine disruptors during pregnancy, work on QSARs dedicated to these substances, and a PBPK model for the zebrafish embryo applied to several families of endocrine disruptors.
At the initiative of the coordinating team and with the involvement of the 11 project partners, several videos have been produced and published on social networks and on the OBERON website, to disseminate as widely as possible the main findings of the project. The videos are aimed at political and regulatory bodies in public health and research, as well as the general public interested in learning more about the effects of endocrine disruptors on health. The videos are available in English and French, with subtitles in English, Spanish, Italian, Czech and Greek.
In particular, the videos address the involvement of endocrine disruptors in liver pathologies (liver disease), obesity, diabetes and health disorders in children.
