The assessments of risks associated with chemical substances resulting from long-term low-dose exposure, which must, in particular, be carried out as part of the study of polluted soils or as part of the impact studies of the regulated environment protection facilities (ICPEs), are constructed in part from physico-chemical, toxicological, ecotoxicological, analytical and regulatory reference data which characterises the chemical substances involved. The Ministry of Ecology – Risks Prevention Directorate (DGPR) – has therefore requested the INERIS to make available to risk assessors, and more generally speaking all players interested in the assessment of these risks, a set of “toxicological and environmental data sheets” intended to comprise an operational tool gathering technical information and data which thereby facilitates risk assessment.
Toxicological and environmental data sheets of chemical substances
The INERIS establishes toxicological and environmental data sheets of chemical substances by first and foremost using published and recognised information of a scientific or regulatory nature. For “existing substances,” within in the meaning of European legislation, monographs published by internationally renowned organisations are examined. Recent data produced by known and recognised independent authors are likewise used.
Acute toxicity threshold reports and records
Within the context of preventing risks associated with accidental emissions of hazardous chemical substances into the atmosphere, risk managers want to have acute toxicity thresholds available. These thresholds are used in studies of the hazards of regulated storage facilities using or producing these substances, in order to determine the “lethal effects radius” (LER) and “irreversible effects radius” (IER) in the event of accidental emissions.
Toxicological reference values
The INERIS is regularly confronted, through its research, technical support, training and critical analysis work, with questions regarding the choice of Reference Toxicological Values (RTV) in the health risk assessments as normally carried out for the impact studies of regulated facilities and the management of polluted soils and sites.